A pill of Imitrex, glass table, razor blade and rolled-up dollar bill... Snorting your triptans might be a reality sooner than we think, independent.co.uk reports.
The idea is pretty simple - a major disadvantage in taking a drug orally is that metabolism in the liver may allow only a portion of the drug into the blood circulation. On the other hand, nasal dosing provides a direct route into the circulation. "Its inner surfaces, all 150 or so square centimetres of them, are rich in tiny veins which offer a direct and rapid way for drugs to get into the circulation."
The research has been going on for a while now and it seems that the pharmas are finally catching up. Here are some of the illnesses that are prime candidates for the nasal delivery of drugs:
- Acute pain
- Seasickness
- Cluster headaches
- Post-operative pain
- Dental pain
- Osteoporosis
- Type 1 diabetes
- Treating symptoms of autism
- Alzheimer's disease
- Boosting libido in women
It might take Big Pharma a while to get us from pill-popping to powder-snorting. However, if it lowers the dosage amount (read - less side effects) and reduces the strain on our livers, it might be worth a switch. Some of you, my gentle readers, are already on "sniffing spree". How is it working out for you? Better than pills? Please do share.
link: Doctor Nose best
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